Inhibition of this cytochrome prevents the cell from using oxygen and forces anaerobic metabolism, resulting in lactate production, cellular hypoxia, and metabolic acidosis. Cyanide binds rapidly with cytochrome a3 in the mitochondria. Inhalation, ingestion or dermal exposure to cyanide-containing compounds may cause cyanide poisoning. Cyanokit contains hydroxocobolamin, the hydroxylated active form of vitamin B 12 ,an antidote indicated for the treatment of cyanide poisoning. ![]() ![]() Cyanokit was FDA approved about a month ago.
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